International Journal of Hematology and Oncology
2025, Vol 35, Num 1 Page(s): 106-110
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A Rare Co-incidental Presentation: Multiple Myeloma and Pleural Adenocarcinoma: A Case Report
Osman YOKUS1, Murat ALBAYRAK2, Ozlem S. BALCIK2, Suleyman S. GOKALP3, Mehmet ERSAYDI3, Mustafa AKAR4, Yucel TEKIN5, Hatice K. BOZKURT5
1Kayseri Education and Research Hospital, Department of Hematology, Kayseri, TURKEY
2Oncology Education and Research Hospital, Department of Hematology, Ankara, TURKEY
3Kayseri Education and Research Hospital, Department of Biochemistry, Kayseri, TURKEY
4Erciyes University Faculty of Medicine, Department of Internal Medicine, Kayseri, TURKEY
5Kayseri Education and Research Hospital, Department of Pathology, Kayseri, TURKEY
Keywords: Multiple myeloma, Pleural adenocarcinoma, Pleural effusion
In this case report we overview the diagnostic and therapeutic approaches for pleural effusions encountered during the treatment and follow-up of patients with myeloma in the light of the current medical literature. A 73-year-old female patient with a stage IIIA multiple myeloma was being treated with melphalan and methyl prednisolone. In the third month of the treatment, she had complaints of coughing, dyspnea and right side pain. Computed tomographic examination of the thorax revealed pleural effusion. Pathological examinations of the pleural fluid and pleural biopsy specimen were compatible with adenocarcinoma. Repeated examinations did not reveal a progression in myeloma or a pleural involvement of myeloma. The patient died of respiratory insufficiency due to the progression of the pleural adenocarcinoma.
Osman YOKUS1, Murat ALBAYRAK2, Ozlem S. BALCIK2, Suleyman S. GOKALP3, Mehmet ERSAYDI3, Mustafa AKAR4, Yucel TEKIN5, Hatice K. BOZKURT5
1Kayseri Education and Research Hospital, Department of Hematology, Kayseri, TURKEY
2Oncology Education and Research Hospital, Department of Hematology, Ankara, TURKEY
3Kayseri Education and Research Hospital, Department of Biochemistry, Kayseri, TURKEY
4Erciyes University Faculty of Medicine, Department of Internal Medicine, Kayseri, TURKEY
5Kayseri Education and Research Hospital, Department of Pathology, Kayseri, TURKEY
Keywords: Multiple myeloma, Pleural adenocarcinoma, Pleural effusion
In this case report we overview the diagnostic and therapeutic approaches for pleural effusions encountered during the treatment and follow-up of patients with myeloma in the light of the current medical literature. A 73-year-old female patient with a stage IIIA multiple myeloma was being treated with melphalan and methyl prednisolone. In the third month of the treatment, she had complaints of coughing, dyspnea and right side pain. Computed tomographic examination of the thorax revealed pleural effusion. Pathological examinations of the pleural fluid and pleural biopsy specimen were compatible with adenocarcinoma. Repeated examinations did not reveal a progression in myeloma or a pleural involvement of myeloma. The patient died of respiratory insufficiency due to the progression of the pleural adenocarcinoma.
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