International Journal of Hematology and Oncology
2025, Vol 35, Num 1 Page(s): 157-162
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Unusual Brain and Temporal Bone Metastases of a Botryoid Type of Embryonal Nasopharyngeal Rhabdomyosarcoma
Mustafa KAZKAYASI1, Fulya KÖYBAŞOĞLU2
1Kırıkkale University Hospital, Department of Otorhinolaryngology, KIRIKKALE
2Ankara Yıldırım Beyazıt Education Hospital, Department of Pathology, ANKARA
Keywords: Embryonal rhabdomyosarcoma, Botryoid type, Nasopharynx, Distant metastasis, Temporal bone
We present a 2 year-old boy with a botryoid type of embryonal nasopharyngeal rhabdomyosarcoma with an unusual outcome. Temporal bone metastasis with brain invasion was detected one year after therapy had been completed. Despite multidisciplinary therapeutic approach, distant metastases occurred in the mastoid and squamous portions of the temporal bone with invasion of the temporal lobe. We review the clinical features of head and neck rhabdomyosarcoma and emphasize the importance of distant tumor metastasis. We believe that this tumor may spread to distant sites by different ways, and its biological course is typically fatal, particularly if recognized in advanced stages.
Mustafa KAZKAYASI1, Fulya KÖYBAŞOĞLU2
1Kırıkkale University Hospital, Department of Otorhinolaryngology, KIRIKKALE
2Ankara Yıldırım Beyazıt Education Hospital, Department of Pathology, ANKARA
Keywords: Embryonal rhabdomyosarcoma, Botryoid type, Nasopharynx, Distant metastasis, Temporal bone
We present a 2 year-old boy with a botryoid type of embryonal nasopharyngeal rhabdomyosarcoma with an unusual outcome. Temporal bone metastasis with brain invasion was detected one year after therapy had been completed. Despite multidisciplinary therapeutic approach, distant metastases occurred in the mastoid and squamous portions of the temporal bone with invasion of the temporal lobe. We review the clinical features of head and neck rhabdomyosarcoma and emphasize the importance of distant tumor metastasis. We believe that this tumor may spread to distant sites by different ways, and its biological course is typically fatal, particularly if recognized in advanced stages.
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