International Journal of Hematology and Oncology
2024, Vol 34, Num 4 Page(s): 159-163
LARGE T-CELL GRANüLER LYMPHOCYTIC LEUCEMIA: A CASE REPORT
ABDURRAHMAN IŞIKDOĞAN1, M. ORHAN AYYILDIZ1, NACİ TİFTİK1, ABDULLAH ALTINTAŞ1, EKREM MÜFTÜOĞLU1
Dicle Üniversitesi Tıp Fakültesi İç Hastalıkları Anabilim Dalı
Keywords: large granular lymphocyte leukemia
LGL-L is a rare disorder characterised by clonal proliferation of cells with large granular lymphocytes. LGL-L can be divided into two major lineage: CD3 ( + ) and CD3 (-) which have distinct clinical and prognostic features. TLGL- L represents 80-85 % of the all LGL-L. The disease has occur in men and women , and principally affects elderly people. Clinical features of T-LGL-L is characterised by recurrent infection related to neutropenia, hepatosplenomegaly and rheumatoid arthritis. Laboratory findings include positive rheumatoid factor and antinuclear antibody. In this case; we discussed a patient with T-LGL-L who admitted to our clinic with fever, arthralgia and piyogenic skin infection.
ABDURRAHMAN IŞIKDOĞAN1, M. ORHAN AYYILDIZ1, NACİ TİFTİK1, ABDULLAH ALTINTAŞ1, EKREM MÜFTÜOĞLU1
Dicle Üniversitesi Tıp Fakültesi İç Hastalıkları Anabilim Dalı
Keywords: large granular lymphocyte leukemia
LGL-L is a rare disorder characterised by clonal proliferation of cells with large granular lymphocytes. LGL-L can be divided into two major lineage: CD3 ( + ) and CD3 (-) which have distinct clinical and prognostic features. TLGL- L represents 80-85 % of the all LGL-L. The disease has occur in men and women , and principally affects elderly people. Clinical features of T-LGL-L is characterised by recurrent infection related to neutropenia, hepatosplenomegaly and rheumatoid arthritis. Laboratory findings include positive rheumatoid factor and antinuclear antibody. In this case; we discussed a patient with T-LGL-L who admitted to our clinic with fever, arthralgia and piyogenic skin infection.