International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 157-159
MULTICENTRIC PLASMA CELL TYPE CASTLEMAN DISEASE: A CASE REPORT
ABDURRAHMAN IŞIKDOĞAN1, ORHAN AYYILDIZ1, MUSTAFA YAKUT1, METİN ÇELİK1
Dicle Üniversitesi Tıp Fakültesi Hematoloji-Onkoloji BD, DİYARBAKIR
Keywords: castleman disease, plasma cell type
Castleman disease is known as giant lymph node hiperplasia or angiofollicular lymph node hiperplasia. It has two histopathologic type; hyalen vascular type (80%) and plasma cell type (20%). Plasma cell type generally has systemic symtomps and has localized and multisentric type. nineteen year-old male was admitted to our clinic with symptoms of fatigue, chest pain and weight loss. Anemia, hepatosplenomegali and right supraclavicular lymhadenopathy were clinical signs. Hemoglobin: 8 gr/dl, erythrocyte sedimentation rate: 86 mm/h, hypoalbuminemia, and policlonal hypergamaglobulinemia were found. Right mediastinal mass was detected. Abdominal ultrasonography revealed hepatosplenomegali and lymphadenopathy in hilum of spleen. Histopathological evaluation of mediastinal lymph node led the diagnosis of plasma cell type Castleman disease. Here we reported a patient with Castleman disease because, it is very rare disease and important in differantial diagnosis of lymphadenopathy.
ABDURRAHMAN IŞIKDOĞAN1, ORHAN AYYILDIZ1, MUSTAFA YAKUT1, METİN ÇELİK1
Dicle Üniversitesi Tıp Fakültesi Hematoloji-Onkoloji BD, DİYARBAKIR
Keywords: castleman disease, plasma cell type
Castleman disease is known as giant lymph node hiperplasia or angiofollicular lymph node hiperplasia. It has two histopathologic type; hyalen vascular type (80%) and plasma cell type (20%). Plasma cell type generally has systemic symtomps and has localized and multisentric type. nineteen year-old male was admitted to our clinic with symptoms of fatigue, chest pain and weight loss. Anemia, hepatosplenomegali and right supraclavicular lymhadenopathy were clinical signs. Hemoglobin: 8 gr/dl, erythrocyte sedimentation rate: 86 mm/h, hypoalbuminemia, and policlonal hypergamaglobulinemia were found. Right mediastinal mass was detected. Abdominal ultrasonography revealed hepatosplenomegali and lymphadenopathy in hilum of spleen. Histopathological evaluation of mediastinal lymph node led the diagnosis of plasma cell type Castleman disease. Here we reported a patient with Castleman disease because, it is very rare disease and important in differantial diagnosis of lymphadenopathy.