International Journal of Hematology and Oncology 2023, Vol 33, Num 4 Page(s): 097-105
A Comparative Study of Low-Profile and Regular Type Totally Implantable Venous Access Devices in Patients with Malignant Tumors: Retrospective Analysis of 4501 Implantations

Ilkay AKMANGIT1, Dogan DEDE1, Ergun DAGLIOGLU2, Bige SAYIN1, Ahmet PEKER3, Dogan UNCU4, Nurullah ZENGİN4

1Ankara Numune Training and Research Hospital, Interventional Radiology Clinics, Ankara, TURKEY
2Ankara Numune Training and Research Hospital, Neurosurgery Clinics, Ankara, TURKEY
3Ankara University Faculty of Medicine, Department of Radiology, Ankara, TURKEY
4Ankara Numune Training and Research Hospital, Medical Oncology Clinics, Ankara, TURKEY

Keywords: Port, TIVAD, Low-profile, Regular, Skin perforation
The purpose of this study was to evaluate safety and efficacy of image-guided radiological totally implantable venous access devices with special reference to rate of skin complications of both regular and low-profile types. 4395 patients were referred to Interventional Radiology Unit between March 2003-September 2013. 4501 implantations of totally implantable venous access device were performed in patients under sonography and fluoroscopy. During this period 2299 regular-type and 2202 low-profile type totally implantable venous access devices were used. Success rate, periprocedural early and long-term complications were evaluated. Periprocedural and early complications of totally implantable venous access devices included 16 (0.4%) arterial punctures, 101 (2.2%) minor hematoma, 1 (%0.02) disconnection of the catheter, 4 (0.09%) septum separation, 38(0.8%) minor erythema-pain and tenderness, 23 (0.5%) short term fever without bacteriemia and 25 (0.6%) inversion of the port. Late complications included 6(0.1%) cellulitis, 8 (0.2%) bacteriemia and sepsis, 305 (6.8%) venous thrombosis, 62 (1.4%) catheter thrombosis, 6 (0.1%) catheter migration and 3 (0.07%) catheter fracture. A total of 53 (1.18%) skin perforation were seen. There was statistically significant difference between regular and low-profile totally implantable venous Access devices particularly in patients with normal and thinner subcutaneous fat tissue (p= 0.024 and <0.001 respectively). The present study is the largest series in the literature in patients with malignant tumors. Image-guided radiological totally implantable venous access device placement is safe and reliable method with a low risk of complications and the results of this study further justify the use of low profile totally implantable venous access device based on lower skin complications.