International Journal of Hematology and Oncology 2023, Vol 33, Num 4 Page(s): 239-244
Seroprevalence of HTLV I-II, HIV and HCV Antibodies in Lymphoma, Head and Neck Cancer Patients

Nuray BUYUKBERBER1, Tulay YALCINKAYA2, Ramazan YILDIZ3, Ugur COSKUN3, Mustafa BENEKLI3

1Gazi University Faculty of Medicine, Department of Medical Microbiology, Ankara, TURKEY
2Turkish National Institute of Health, Microbiology Reference Laboratory, Ankara, TURKEY
3Gazi University Faculty of Medicine, Department of Medical Oncology, Ankara, TURKEY

Keywords: HTLV, HIV, HCV, Lymphoma, Head and neck carcinoma
Human T-cell lymphotropic virus type I (HTLV I), which has a worldwide distribution, is the first human retrovirus mainly to be associated with malignant diseases, such as adult T-cell leukemia-lymphoma and bronchioloalveolar carcinoma. Tip II (HTLV II), a retrovirus having genomic homology with the HTLV I, has not been proven to be a pathogenic virus so far. Hepatitis C virus (HCV), an RNA virus, is the cause of acute and chronic hepatitis, cirrhosis and liver cancer. Human immunodeficiency virus (HIV syn. HTLV III), is a factor in AIDS. Studies on the development of malignant diseases of these viruses are restricted in all over the world, there is no detailed study was found in our country as well. In this study, the seropositivity of HTLV I-II, HIV and HCV viruses in lymphoma and head and neck cancer patients and the relationship between these viruses and these cancers evaluated. As a result HTLV I-II seropositivity was found in 2 of 86 lymphoma and 2 of 80 head and neck cancer patients. There is a need for further large studies related to those and other viral agents caused malignancies.