International Journal of Hematology and Oncology 2024, Vol 34, Num 3 Page(s): 175-181
“Vanishing Cancer Phenomenon” in Endometrial Cancers: A Report of Three Cases and Review of the Literature

Mehmet KARACA1, Ali AYHAN2, Polat DURSUN2

1Kafkas University Faculty of Medicine, Department of Obstetrics and Gynecology, Kars, TURKEY
2Baskent University Faculty of Medicine, Department of Obstetrics and Gynecology, Ankara, TURKEY

Keywords: Endometrial Carcinoma, No Residual Tumor, Vanishing Cancer Phenomenon, Vanishing Carcinoma
“Vanishing carcinoma” phenomenon has previously reported and accepted on prostate cancer cases as a distinct clinicopathological entity in uro-pathology. However, although it may be seen in cervical and endometrial carcinoma, it has not been evaluated by extensively in gynecology literature. This review has evaluated the ‘’vanishing endometrial carcinoma’’ phenomenon through observing three similar cases and available literature reports. With this respect, causes and occurrence rates of the ‘’vanishing endometrial carcinoma’’ has been discussed. Also, clinical indications including stage and prognosis of the disease have been evaluated, and suggestions have been made on how to determine if it is a really vanishing case. In conclusion, recognition of the concept, the vanishing endometrial carcinoma, might be a useful for gynecologic pathologist and gynecologic oncologist in order to prevent mismanagement and medico-legal ligitation.