International Journal of Hematology and Oncology
2025, Vol 35, Num 1 Page(s): 137-140
| Back | Table of Contents | Turkish Abstract | PDF | Mail to Author | |
ACQUIRED GLANZMANN THROMBASTENIA DUE TO IMMUNE THROMBOCITOPENIC PURPURA
Abdullah ALTINTAŞ1, Orhan AYYILDIZ1, Murat SÖKER2, Ekrem MÜFTÜOĞLU1
Keywords: Acquired Glanzmann thrombasthenia, Immune thrombocytopenic purpura
Glanzmann thrombastenia is a rare otosomal ressesive disease which has normal platelet count and morphology, and impairment of platelet aggregation. There is qualitative or quantitative abnormality in GPIIb-IIIa proteins that have a function of receptor to fibrinogen and Von-Willebrand Factor. Mucocutenous hemorrhage, epistaxis,gingival hemorrhage, and hemorrhage were seen especially in young age. The disease may occur rarely as an acquired. Autoantibodies developed in the course of some disease such as Non-hodgkin’s lymphoma, Hodgkin disease, multiple myeloma, in patients who are taking immunusuppressive drugs, and particularly in immune thrombocytopenic purpura. We report here, a patient 42 years-old female, who is diagnosed as Acquired Glanzmann thrombastenia due to immune thrombocytopenia.
Abdullah ALTINTAŞ1, Orhan AYYILDIZ1, Murat SÖKER2, Ekrem MÜFTÜOĞLU1
Keywords: Acquired Glanzmann thrombasthenia, Immune thrombocytopenic purpura
Glanzmann thrombastenia is a rare otosomal ressesive disease which has normal platelet count and morphology, and impairment of platelet aggregation. There is qualitative or quantitative abnormality in GPIIb-IIIa proteins that have a function of receptor to fibrinogen and Von-Willebrand Factor. Mucocutenous hemorrhage, epistaxis,gingival hemorrhage, and hemorrhage were seen especially in young age. The disease may occur rarely as an acquired. Autoantibodies developed in the course of some disease such as Non-hodgkin’s lymphoma, Hodgkin disease, multiple myeloma, in patients who are taking immunusuppressive drugs, and particularly in immune thrombocytopenic purpura. We report here, a patient 42 years-old female, who is diagnosed as Acquired Glanzmann thrombastenia due to immune thrombocytopenia.
| Back | Table of Contents | Turkish Abstract | PDF | Mail to Author | |