International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 048-056
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STEM CELL PLASTICITY AND STEM CELL TREATMENT IN CLINICAL PRACTICE
Fahri ŞAHİN1, Güray SAYDAM1, Serdar Bedii OMAY1
Ege Üniversitesi Tıp Fakültesi, Hematoloji Bilim Dalı, İZMİR
Keywords: Adult stem cells, Plasticity, Clinical applications
It has been known for decades that stem cells with limited differentiation potential are present in post-natal tissues of mammals, and adult stem cells are already clinically. Recent studies report that adult tissues might contain cells with pluripotent characteristics. Stem cells are being investigated for their potential use in regenerative medicine. A series of remarkable studies suggested that adult stem cells undergo novel patterns of development by a process to as transdifferentiation or plasticity. Especially repairing the vulnerable and normally non-regenerative tissues and organs such as neurons and heart tissue by stem cells are going to be promising treatment modalities in the future. In this review article, we summarized the recent developments in stem cell characteristics and practical application in clinical area by using our own instutitional experience.
Fahri ŞAHİN1, Güray SAYDAM1, Serdar Bedii OMAY1
Ege Üniversitesi Tıp Fakültesi, Hematoloji Bilim Dalı, İZMİR
Keywords: Adult stem cells, Plasticity, Clinical applications
It has been known for decades that stem cells with limited differentiation potential are present in post-natal tissues of mammals, and adult stem cells are already clinically. Recent studies report that adult tissues might contain cells with pluripotent characteristics. Stem cells are being investigated for their potential use in regenerative medicine. A series of remarkable studies suggested that adult stem cells undergo novel patterns of development by a process to as transdifferentiation or plasticity. Especially repairing the vulnerable and normally non-regenerative tissues and organs such as neurons and heart tissue by stem cells are going to be promising treatment modalities in the future. In this review article, we summarized the recent developments in stem cell characteristics and practical application in clinical area by using our own instutitional experience.
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