International Journal of Hematology and Oncology 2019, Vol 29, Num 3 Page(s): 016-021
SINGLE (500 CGY, 800 CGY) AND MULTIFRACTION (300X10 CGY) RADIOTHERAPY SCHEDULES IN THE TREATMENT OF PAINFUL BONE METASTASES

MUZAFFER BEDRİ ALTUNDAĞ1, ALİ RIZA ÜÇER1, TAMER ÇALİKOĞLU1, ZEKİ GURAN1

Ankara Onkoloji Hastanesi, Radyasyon Onkolojisi Kliniği, ANKARA

Keywords: bone metastases, palliation, radiotherapy, single dose
Painful bone metastatic patients were treated with three randomised different dose and fractions from May 1996 to March 1997 at the Ankara Oncology Hospital. This study compares low single dose (500 cGy) which to date have not been documented, high single dose (800 cGy) which during the last couple of years have been our preference and the traditional multifraction dose (300x10 cGy). A total of 42 patients and 49 fields were evaluated. Their ages ranged from 16-73 years, 29 of those were females of whom 69% had a primary histopathology of breast cancer. The average follow-up period was 303 days. From the administrated doses, namely 500 cGy, 800 cGy and 300x10 cGy, 72%, 76% and 86% of the patients had either complete or partial response respectively. The response rates among the treatment doses were statistically insignificant. Considering the socioeconomic position of our country, the high patient machine ratio and the lack of many radiotherapy centres. patients without a long life expectancy will painful metastatic bone cancer can be effectively treated with a single dose schedule.