International Journal of Hematology and Oncology 2019, Vol 29, Num 3 Page(s): 43-52
Prognostic Factors Affecting Survival in Patients with Ovarian Cancer: A 5-Year Experience in an University Hospital

Gül PINAR1, Tevfik PINAR2, Ayşe DURUKAN1, Ali AYHAN3

1Yıldırım Beyazıt University, Faculty of Health Sciences, Department of Nursing, Ankara, TURKEY
2Hacettepe University, Institute of Public Health, Ankara, TURKEY
3Baskent University Ankara Hospital, GyneOncologic Clinic, Ankara, TURKEY

Keywords: Ovarian cancer, 5-year survival, Prognostic factors
The aim if this study is to explore the impact of the various prognostic factors on overall survival in women with ovarian cancer (OC). Patients diagnosed with gynecologic malignancy in Gynecology Clinic of Baskent University Medicine Faculty between 2010 and 2015 included to study. Patients with ovarian (n= 112) cancers examined retrospectively. Kaplan-Meier, Univariate and Multivariate Cox regression model were performed to estimate for associations of potential variables with survival factors. The mean patient age was 56.4 y, range 20-80. The overall survival was 94.3%, 83.4%, 66.4%, 54.7% and 42.8% at 1, 2 3, 4 and 5 years respectively (60.5 months, range 43-68). 3-year disease-free survival was 25.3% (18.3 months, range 17-20). Multivariate analysis of patients indicated that stage, histology, grade, age at diagnosis, comorbidity, recurrence, BMI, menopausal status and regional distance were independent prognostic factors on survival (p< 0.05). In conclusion, these results will presents a framework to identify fundamental causes in survival for OC.