International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 092-094
NEUTROPENIC ENTEROCOLITIS IN A CHILD WITH ACUTE MYELOBLASTIC LEUKEMIA PRIOR TO ADMINISTRATION OF CHEMOTHERAPY
HASAN TEZER1, YUSUF ZİYA ARAL1, ŞENAY SAVAŞ1, YILDIZ DALLAR1
S.B. Ankara Eğitim ve Araştırma Hastanesi Çocuk Kliniği, ANKARA
Keywords: neutropenic enterocolitis, typhlitis, acute myeloblastic leukemia, child
Neutropenic enterocolitis is an acute, life threatening condition, often seen in children with malignancies who are receiving chemotherapy. The occurrence of this complication in the absence of chemotherapy is very rare, with only one reported case in acute myeloblastic leukemia(AML). An 11-year-old boy diagnosed AML-M4 receiving antibiotics due to neutropenic fever developed severe abdominal pain, diarrhea, and vomiting and neutropenic enterocolitis was diagnosed by ultrasonography and tomography. Blood culture grew Enterococcus faecium. This patient was successfully treated with cessation of oral nutrition, gastrointestinal decompression, antibiotic therapy, partial parenteral nutrition and transfusion of blood product. Neutropenic enterocolitis must also be considered in the differential diagnosis of abdominal pain in patients with untreated leukemia.
HASAN TEZER1, YUSUF ZİYA ARAL1, ŞENAY SAVAŞ1, YILDIZ DALLAR1
S.B. Ankara Eğitim ve Araştırma Hastanesi Çocuk Kliniği, ANKARA
Keywords: neutropenic enterocolitis, typhlitis, acute myeloblastic leukemia, child
Neutropenic enterocolitis is an acute, life threatening condition, often seen in children with malignancies who are receiving chemotherapy. The occurrence of this complication in the absence of chemotherapy is very rare, with only one reported case in acute myeloblastic leukemia(AML). An 11-year-old boy diagnosed AML-M4 receiving antibiotics due to neutropenic fever developed severe abdominal pain, diarrhea, and vomiting and neutropenic enterocolitis was diagnosed by ultrasonography and tomography. Blood culture grew Enterococcus faecium. This patient was successfully treated with cessation of oral nutrition, gastrointestinal decompression, antibiotic therapy, partial parenteral nutrition and transfusion of blood product. Neutropenic enterocolitis must also be considered in the differential diagnosis of abdominal pain in patients with untreated leukemia.