International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 072-078
RADIOTHERAPY RESULTS IN ADULT GLIAL TUMORS: RETROSPECTIVE ANALYSIS OF 73 PATIENTS
MELEK NUR YAVUZ1, A AYDIN YAVUZ1, MİNE GENÇ1, EDA KÜÇÜKTÜLÜ1, FATMA ÇOLAK1, ZÜMRÜT BAHAT1, EMEL ÇİMŞİTOĞLU1
Karadeniz teknik Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi AD, TRABZON
Keywords: glial tumor, radiotherapy
Treatment results and prognostic factors of eighty-five adult patients with the diagnosis of glial tumor who were treated at Karadeniz Technical University, Department of Radiation Oncology, between January 1996 and June 2002 were retrospectively analyzed. Using teletherapy machines (Cobalt 60 and 6-10 MV lineer accelerator) 54 Gy in low-grade tumors and 60-66 Gy in high-grade tumors were given to local fields. The survival rates at 2 years are 80% for WHO grade I, 58% for WHO grade II, 23% for WHO grade 3 and 17% for grade IV, 75% for oligodendroglima, 50% for anaplastic oligodendroglioma. While only duration of semptom was statistically significant prognostic factor in terms of overall survival for patients with high grade astrocytomas (p=0.005) on multivariate analysis, no significant prognostic factor was shown to be statistically important for low grade tumors. These results are the first report from the Eastern Blacksea region of Turkey, and are compatible with the relevant literature.
MELEK NUR YAVUZ1, A AYDIN YAVUZ1, MİNE GENÇ1, EDA KÜÇÜKTÜLÜ1, FATMA ÇOLAK1, ZÜMRÜT BAHAT1, EMEL ÇİMŞİTOĞLU1
Karadeniz teknik Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi AD, TRABZON
Keywords: glial tumor, radiotherapy
Treatment results and prognostic factors of eighty-five adult patients with the diagnosis of glial tumor who were treated at Karadeniz Technical University, Department of Radiation Oncology, between January 1996 and June 2002 were retrospectively analyzed. Using teletherapy machines (Cobalt 60 and 6-10 MV lineer accelerator) 54 Gy in low-grade tumors and 60-66 Gy in high-grade tumors were given to local fields. The survival rates at 2 years are 80% for WHO grade I, 58% for WHO grade II, 23% for WHO grade 3 and 17% for grade IV, 75% for oligodendroglima, 50% for anaplastic oligodendroglioma. While only duration of semptom was statistically significant prognostic factor in terms of overall survival for patients with high grade astrocytomas (p=0.005) on multivariate analysis, no significant prognostic factor was shown to be statistically important for low grade tumors. These results are the first report from the Eastern Blacksea region of Turkey, and are compatible with the relevant literature.