International Journal of Hematology and Oncology 2019, Vol 29, Num 1 Page(s): 107-112
Management of Arteriovenous Malformations by Stereotactic Radiosurgery: A Single Center Experience

Ferhat DINCOGLAN1, Omer SAGER1, Hakan GAMSIZ1, Selcuk DEMIRAL1, Bora UYSAL1, Serdar SURENKOK1, Sait SIRIN2, Kaan OYSUL1, Murat BEYZADEOGLU1

1Gulhane Military Medical Academy, Department of Radiation Oncology, Ankara, TURKEY
2Gulhane Military Medical Academy, Department of Neurosurgery, Ankara, TURKEY

Keywords: Arteriovenous malformation, Stereotactic radiosurgery, Spetzler-Martin grading, SRS, Hemorrhage
The aim of this monoinstitutional study is to evaluate the efficiency of stereotactic radiosurgery (SRS) in the management of arteriovenous malformations (AVM). Between June 1998 and July 2011, 51 patients with AVM were treated with linear accelerator-based SRS at our department. All patients were preevaluated for AVM size, location, neurological status, previous history of hemorrhage and Spetzler-Martin grading. Treated patients then underwent follow-up to evaluate obliteration and clinical status. Median followup time was 32 months (range; 20-93 months). Spetzler-Martin grade I-II and AVM sizes below 3 cm were associated with increased obliteration rate (p=0.01). The annual hemorrhage risk was 1.9%. No patients experienced deterioration of neurological status at follow-up. LINAC-based SRS is a safe and effective treatment modality in the management of cerebral AVMs. SRS comprises an effective alternative to surgery for the treatment of particularly small AVMs inaccessible with surgery.