International Journal of Hematology and Oncology 2022, Vol 32, Num 3 Page(s): 001-009
Role and Alternative Modalities of External Beam Radiotherapy in the Management of Retinoblastoma

Berrin PEHLIVAN1, Erkan TOPKAN1, Cem ONAL1, Melek YAVUZ1

Baskent University Faculty of Medicine, Adana Medical and Research Center, Kisla Campus, Adana, TURKEY

Keywords: Retinoblastoma, External beam radiotherapy, Toxicity, Chemotherapy, Secondary malignancy
Retinoblastoma (RB) is the most common orbital tumor of childhood. Treatment strategy depends on number, loalization and extent of disease (unilateral vs bilateral) involvement. Currently, significant improvements in treatment and long survival rates have been achieved in management of this tumor group that mandates for search of more sophisticated novel treatment modalities to reduce the risks of treatment related side effects and secondary malignancies. In recent years, both the role and techniques of radiation therapy (RT) have significantly changed in parallel to the improvements in technology. Present review aims to discuss the current treatment modalities in RB, and the role and alternative techniques of RT in the light of recent literature.