International Journal of Hematology and Oncology 2022, Vol 32, Num 4 Page(s): 046-050
Unusual Extramedullary Recurrence and Renal Relapse Despite Complete Chimerysm after Allografting in Ph+ ALL

Songul SEREFHANOGLU1, Hakan GOKER1, Dilek E. BAYDAR2, Aysegul UNER2, Mustafa ARICI3, Ibrahım C. HAZNEDAROGLU1, Yahya BUYUKASIK1, Nılgun SAYINALP1, Salıh AKSU1, Osman I. OZCEBE1

1Hacettepe University Faculty of Medicine, Department of Internal Medicine, Division of Hematology, Ankara, TURKEY
2Hacettepe University Faculty of Medicine, Department of Pathology, Ankara, TURKEY
3Hacettepe University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Ankara, TURKEY

Keywords: ALL, Renal relapse, Allogeneic stem cell transplantation, Complete chimerism
Extramedullary recurrences with or without bone marrow involvement are reported in up to a half of leukemic relapses after bone marrow transplantation. Extramedullary relapse of acute lymphoblastic leukemia (ALL) in the kidney after allogeneic stem cell transplantation (allo-SCT) is rare. We herein, report an additional case with extramedullary recurrences and renal relapse after first-allografting for Ph+-acute lymphoblastic leukemia. He had no evidence of leukemia in his marrow demonstrating 98% full-donor chimerism while he had ALL relapse in his kidney.