International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 223-229
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Histopathological Characteristics may not be Useful in the Differential Diagnosis Between Basal Cell Carcinoma and Benign Tumors of Cutaneous Appandages Originating from Hair Follicle
Ilker SENGUL1, Demet SENGUL2, Muzeyyen H. ASTARCI3, Huseyin USTUN3
1Giresun University Faculty of Medicine, Department of General Surgery, Giresun, TURKEY
2Prof. Dr. A. Ilhan Ozdemir State Hospital, Department of Pathology, Giresun, TURKEY
3Ankara Training and Research Hospital, Department of Pathology, Ankara, TURKEY
Keywords: Basal cell, Pigmentation, Inflammation, Histopathology
Differential diagnosis between benign tumors of cutaneous appandages originating from hair follicle (BTCOHF) (trichoadenoma [TA], trichofolliculoma [TF], trichoepithelioma [TE] and trichoblastoma [TB]) and basal cell carcinoma (BCC) have been tedious for the pathologists, especially in the presence of small specimens to date. Thirty cases of BTCOHF and 30 cases of BCC were retrieved from the archives, deposited from 2004 to 2008. Age, sex, localisation and histopathological characters such as ulceration, pigmentation, inflammation, and cyst formation were comparatively evaluated between both groups and each subgroups. No significant diference was detetected between two groups in the rate of the age, sex and the histopathology. Besides, histopathological characters were not significant for the subgroups of BCC. However, ulceration was observed in TE (Of 21 cases 5, [23.8 %]) and TB (All the 5 cases, [100 %]), but not in TA and TF which are the subgroups of BTCOHF and the difference was significant (p = 0,005). But, pigmentation, inflammation and cyst formation were not significant among the subgroups of both groups. We can conclude that BCC and BTCOHF may not be discriminated concerning age, sex and histopathological characters including ulceration, pigmentation, inflammation, and cyst formation. Secondly, one may not make the differential diagnosis easily even between the subgroups of each group via evaluating the histopathological characters, so that might create some life-threatening unwelcome outcomes.
Ilker SENGUL1, Demet SENGUL2, Muzeyyen H. ASTARCI3, Huseyin USTUN3
1Giresun University Faculty of Medicine, Department of General Surgery, Giresun, TURKEY
2Prof. Dr. A. Ilhan Ozdemir State Hospital, Department of Pathology, Giresun, TURKEY
3Ankara Training and Research Hospital, Department of Pathology, Ankara, TURKEY
Keywords: Basal cell, Pigmentation, Inflammation, Histopathology
Differential diagnosis between benign tumors of cutaneous appandages originating from hair follicle (BTCOHF) (trichoadenoma [TA], trichofolliculoma [TF], trichoepithelioma [TE] and trichoblastoma [TB]) and basal cell carcinoma (BCC) have been tedious for the pathologists, especially in the presence of small specimens to date. Thirty cases of BTCOHF and 30 cases of BCC were retrieved from the archives, deposited from 2004 to 2008. Age, sex, localisation and histopathological characters such as ulceration, pigmentation, inflammation, and cyst formation were comparatively evaluated between both groups and each subgroups. No significant diference was detetected between two groups in the rate of the age, sex and the histopathology. Besides, histopathological characters were not significant for the subgroups of BCC. However, ulceration was observed in TE (Of 21 cases 5, [23.8 %]) and TB (All the 5 cases, [100 %]), but not in TA and TF which are the subgroups of BTCOHF and the difference was significant (p = 0,005). But, pigmentation, inflammation and cyst formation were not significant among the subgroups of both groups. We can conclude that BCC and BTCOHF may not be discriminated concerning age, sex and histopathological characters including ulceration, pigmentation, inflammation, and cyst formation. Secondly, one may not make the differential diagnosis easily even between the subgroups of each group via evaluating the histopathological characters, so that might create some life-threatening unwelcome outcomes.
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