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The Overview of Diagnostic Criteria and Treatment Options of Transplantation Associated Thrombotic Microangiopathy with Two Case Reports

Fatih ERBEY¹, Ibrahim BAYRAM¹, Sema YILMAZ¹, Atila TANYELI¹

Cukurova University Faculty of Medicine, Department of Pediatric Oncology and Pediatric Bone Marrow Transplantation Unit, Adana, TURKEY

Keywords: Transplantation, Microangiopathy, Childhood

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Transplantation associated thrombotic microangiopathy has been considered to be a severe complication of hematopoietic stem cell transplantation. Although there has been an agreement in terms of transplantation associated thrombotic microangiopathy criteria, treatment options has not been clarified yet. Therefore we want to present two patients aged 5 years and 13 years who developed transplantation associated thrombotic microangiopathy after allogenic peripheric stem cell transplantation and to discuss both diagnostic criteria and treatment options of transplantation associated thrombotic microangiopathy.

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