International Journal of Hematology and Oncology 2020, Vol 30, Num 3 Page(s): 180-183
Richter's Transformation; the Cause of Fever of Unknown Origin in a Case with Chronic Lymphocytic Leukemia

Behice KURTARAN1, Semra PAYDAS2, Sinan YAVUZ2, Aslıhan CANDEVİR1

1Cukurova University Faculty of Medicine, Department of Infectious Disease, Adana, TURKEY
2Cukurova University Faculty of Medicine, Department of Medical Oncology, Adana, TURKEY

Keywords: Chronic lymphocytic leukemia (CLL), Fever of unkonown origin (FUO), Richter transformation (RT)
Chronic lymphocytic leukemia (CLL) is the most common leukemia in many countries. Infections are the most common causes of morbidity and mortality; lymphoid cell dysfunction and neutropenia associated with chemotherapy are main predisposing conditions for infection. For this reason infectious conditions must be excluded in a case with CLL and fever. Richter’s transformation (RT) is a kind of lymphoma that is a rare condition in CLL cases Fever of unknown origin is a rare finding in Richter’s transformation (RT) but it has been reported as anecdotal reports. Here a case with RT as the cause of fever in a case with CLL was reported and literature was reviewed.