International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 116-120
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The Development of Chronic Myelogenous Leukemia in a Patient with Malign Fibrous Histiositom Treated with Radiotherapy: Case Report
Elif AKDOĞAN1, Mehmet SÖNMEZ1, Mustafa YILMAZ1, Ahmet DURMUŞ1, Ercüment OVALI1, Serdar B. OMAY1
Karadeniz Teknik Üniversitesi Tıp Fakültesi, Hematoloji Bilim Dalı, TRABZON
Keywords: Radiotherapy, CML, MFH
Thirty three years old women was treated with surgery and subsequent radiotherapy for diagnosis of malign fibrous histiosarcom (MFH) on left upper leg. She achived complete remission. 6 years later asymptomatic leukocytosis occured. Analysis using RT-PCR did show bcr-abl transcript. She was diagnosed chronic myelogenous leukemia (CML). Secondary malignancy like CML is one of the rare late complication of radiotherapy. We report here, a case who is diagnosed CML 6 years later after treatment with radiotherapy.
Elif AKDOĞAN1, Mehmet SÖNMEZ1, Mustafa YILMAZ1, Ahmet DURMUŞ1, Ercüment OVALI1, Serdar B. OMAY1
Karadeniz Teknik Üniversitesi Tıp Fakültesi, Hematoloji Bilim Dalı, TRABZON
Keywords: Radiotherapy, CML, MFH
Thirty three years old women was treated with surgery and subsequent radiotherapy for diagnosis of malign fibrous histiosarcom (MFH) on left upper leg. She achived complete remission. 6 years later asymptomatic leukocytosis occured. Analysis using RT-PCR did show bcr-abl transcript. She was diagnosed chronic myelogenous leukemia (CML). Secondary malignancy like CML is one of the rare late complication of radiotherapy. We report here, a case who is diagnosed CML 6 years later after treatment with radiotherapy.
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