International Journal of Hematology and Oncology 2018, Vol 28, Num 3 Page(s): 215-220
Radiotherapy Results of Stage T2(T2a-bN0M0) Bladder Carcinoma

Yeşim ELGİN1, Bülent KÜÇÜKPLAKÇI1, Ergun SANRI1, Aytül ÖZGEN1, Cem MISIRLIOĞLU1, Taciser DEMİRKASIMOĞLU1, V. Işıl UĞUR1, Tijen YÖRÜKOĞLU1, Ş.Pınar KARA1, Nadi ÖZDAMAR1

Sağlık Bakanlığı Ankara Onkoloji Hastanesi Radyasyon Onkolojisi Kliniği, ANKARA

Keywords: Invasive bladder carcinoma, Radiotherapy, Chemotherapy
A total of 64 stage T2 patients with bladder carcinoma who admitted to our clinic between January 2000 and December 2004, were analysed retrospectively. Median age was 66 years, 55 of patients were male and 9 were female. Histopathology was found transitional cell carcinoma in 61 (95.3%) patients and more than half of patients have high grade histopathology. Transurethral resection was the choice of surgery in 50 (78%) patients and open tumor resection in 10 patients, partial or total cystectomy in 2 and punch biopsy in 2 patients. Before radiotherapy, 12 cases were treated with various chemotherapy protocols. In survival analysis, 43 patients were assessed. Radiotherapy was applied in 36 patients with curative intent, in 7 patients with palliative intent because of progressive disease. The overall 1, 2, 3 and 5 year survival rates were 72%, 53%, 49% and 38% respectively. Median survival was 43 months. The prognostic value of patient and tumor related factors, such as age, gender, pathology, grade, tumor size, tumor location, type of surgery, chemotherapy has been studied and none of them was found statistically significant. Eigtheen patients (42%) were still alive at the time of analysis.