International Journal of Hematology and Oncology 2019, Vol 29, Num 4 Page(s): 113-118
MULTIPLE MYELOMA AND HEMOSTATIC ALTERATIONS

MUSTAFA ÖZDOĞAN1, ERKAN ÇOBAN1, LEVENT ÜNDAR1

Akdeniz Üniv. Tıp Fak. Onkoloji BD

Keywords: multiple myeloma, hemostatic alterations
Multiple myeloma is recognized clinically by the proliferation of malignant plasma cells in the bone marrow, the detection of a serum or urine monoclonal protein, anemia, hypercalcemia, renal insufficiency, and lytic bone lesions. Patients with multiple myeloma can manifest hemostatic alterations. Alteration of hemostasis in multiple myeloma are expressed as either hemorrhage or thrombosis, or a combination of the two; however, hemorrhage is more common than thrombosis. The etiopathogenesis of hemostatic alterations in multiple myeloma is multifactorial.