International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 234-240
USE OF BISPHOSPHANATES IN ONCOLOGY
MUSTAFA KADRİ ALTUNDAĞ1, CUMALİ GÖKÇE1, H. İBRAHİM GÜLLÜ1
Hacettepe Üniversitesi Onkoloji Enstitüsü
Keywords: bisphosphanates, bone metastases, hypercalcemia
Bisphosphanates are potent inhibitors of tumor-induced osteoclast-mediated bone resorption. The clinical use of bisphosphanates has increased dramatically during the past five years. They now constitute the standard treatment for cancer hypercalcemia. Bisphosphanate use is a major therapeutic advance in the management of the skeletal morbidity caused by metastatic breast cancer or multiple myeloma. The use of bisphosphanates to prevent bone metastases remain experimental.
MUSTAFA KADRİ ALTUNDAĞ1, CUMALİ GÖKÇE1, H. İBRAHİM GÜLLÜ1
Hacettepe Üniversitesi Onkoloji Enstitüsü
Keywords: bisphosphanates, bone metastases, hypercalcemia
Bisphosphanates are potent inhibitors of tumor-induced osteoclast-mediated bone resorption. The clinical use of bisphosphanates has increased dramatically during the past five years. They now constitute the standard treatment for cancer hypercalcemia. Bisphosphanate use is a major therapeutic advance in the management of the skeletal morbidity caused by metastatic breast cancer or multiple myeloma. The use of bisphosphanates to prevent bone metastases remain experimental.