International Journal of Hematology and Oncology 2023, Vol 33, Num 4 Page(s): 047-051
THREE CASES WITH LANGERHANS CELL HISTIOCYTOSIS WITH SISTEMIC INVOLVEMENT

YAVUZ KÖKSAL1, ABDÜLGANİ GÜLYÜZ1, ÜMRAN ÇALIŞKAN1, İSMAİL REİSLİ1, CANAN UÇAR1

Selçuk Üniversitesi Meram Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları AD

Keywords: langerhans cell histiocytosis, childhood, liver, lung, thymus
Histiocytosis which is a proliferative process characterized by an accumulation of dentritic cells in various tissues and organs is a rare disease. It can occur as an isolated lesion or as widespread systemic disease involving virtually any body site. Langerhans cell histiocytosis was diagnosed by light microscopy in a 27-month-old boy and 16-month-old girl with anemia hepatosplenomegaly, exanthema and lesions on the skull and a 9-month-old girl with thymic and cutaneous involvement. Clinical and laboratory findings of the cases are discussed in the light of literature.