International Journal of Hematology and Oncology 2021, Vol 31, Num 4 Page(s): 159-163
LARGE T-CELL GRANüLER LYMPHOCYTIC LEUCEMIA: A CASE REPORT

ABDURRAHMAN IŞIKDOĞAN1, M. ORHAN AYYILDIZ1, NACİ TİFTİK1, ABDULLAH ALTINTAŞ1, EKREM MÜFTÜOĞLU1

Dicle Üniversitesi Tıp Fakültesi İç Hastalıkları Anabilim Dalı

Keywords: large granular lymphocyte leukemia
LGL-L is a rare disorder characterised by clonal proliferation of cells with large granular lymphocytes. LGL-L can be divided into two major lineage: CD3 ( + ) and CD3 (-) which have distinct clinical and prognostic features. TLGL- L represents 80-85 % of the all LGL-L. The disease has occur in men and women , and principally affects elderly people. Clinical features of T-LGL-L is characterised by recurrent infection related to neutropenia, hepatosplenomegaly and rheumatoid arthritis. Laboratory findings include positive rheumatoid factor and antinuclear antibody. In this case; we discussed a patient with T-LGL-L who admitted to our clinic with fever, arthralgia and piyogenic skin infection.