International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 126-132
COMPARISON OF THE PRIMARY NODAL AND EXTRANODAL LYMPHOMAS: CLINICAL, HISTOPATHOLOGICAL CHARACTERISTICS AND SURVIVAL
BÜLENT ESER1, MUSTAFA ÇETİN1, ALİ ÜNAL1, OLGUN KONTAŞ1
Erciyes Üniversitesi Tıp Fakültesi Hematoloji Bilim Dalı
Keywords: non-hodgkin lymphoma, extranodal, survival
The aim of this study is to compare clinic, histopathologic characteristics and survival of the patients with primary extranodal and nodal non-Hodgkin's lymphomas. A total of 196 patients diagnosed as non-Hodgkin's lymphoma between January 1990 and August 2000 were evaluated retrospectively. Primary extranodal involvement was detected in 89 (45,4%) patients. Male to female ratio, median age and ratio of patients above 60 years were more frequent in nodal lymphoma, but stage III-IV disease and aggressive histopathology were higher in extranodal lymphoma patients. Diffuse large cell lymphoma was the most commonly observed histopathological type. In a median 13 months (range;2-130) follow-up period, survival was not significantly different between nodal and primary extranodal lymphomas (three year survival rates were: 81.5% and 76.1%, respectively). Three-year survival rates were also found to be equal (%73.1 and %71.5) among patients who had aggressive histopathology. In conclusion; the frequency of primary extranodal non-Hodgkin's lymphoma is higher in our patient group compared to current than literature. In addition, primary extranodal presentation did not adversely affect survival rate in this group.
BÜLENT ESER1, MUSTAFA ÇETİN1, ALİ ÜNAL1, OLGUN KONTAŞ1
Erciyes Üniversitesi Tıp Fakültesi Hematoloji Bilim Dalı
Keywords: non-hodgkin lymphoma, extranodal, survival
The aim of this study is to compare clinic, histopathologic characteristics and survival of the patients with primary extranodal and nodal non-Hodgkin's lymphomas. A total of 196 patients diagnosed as non-Hodgkin's lymphoma between January 1990 and August 2000 were evaluated retrospectively. Primary extranodal involvement was detected in 89 (45,4%) patients. Male to female ratio, median age and ratio of patients above 60 years were more frequent in nodal lymphoma, but stage III-IV disease and aggressive histopathology were higher in extranodal lymphoma patients. Diffuse large cell lymphoma was the most commonly observed histopathological type. In a median 13 months (range;2-130) follow-up period, survival was not significantly different between nodal and primary extranodal lymphomas (three year survival rates were: 81.5% and 76.1%, respectively). Three-year survival rates were also found to be equal (%73.1 and %71.5) among patients who had aggressive histopathology. In conclusion; the frequency of primary extranodal non-Hodgkin's lymphoma is higher in our patient group compared to current than literature. In addition, primary extranodal presentation did not adversely affect survival rate in this group.