International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 091-094
THE COEXISTENCE OF BREAST CANCER AND CHRONIC LYMPHOCYTIC LEUKEMIA: CASE REPORT
BÜLENT KARABULUT1, GÜRAY SAYDAM1, MUSTAFA ÖZMEN1, ULUS ALİ ŞANLİ1, CANFEZA SEZGİN1, MİNE HEKİMGİL1, RÜÇHAN USLU1, ERDEM GÖKER1, FİLİZ BÜYÜKKEÇECİ1
Ege Üniversitesi Tip Fakültesi Hastanesi İç Hastalıkları Ana Bilim Dalı, İZMİR
Keywords: breast cancer, chronic lymphocytic leukemia
It is a rare phenomenon to detect the second malignancy in the course of malignant disease. The risk of secondary malignancy in CLL patients is significantly higher than normal population. Also, CLL can be detected as secondary malignancy in the course of other malignant diseases. In such cases, the common ethiological agent can be considered. In this report, we present a case who was diagnosed as breast cancer in 1996. After surgical resection, the patient was treated with radiotherapy and chemotherapy. During the follow-up period, lymphocytosis in peripheral blood and mature lymphocyte infiltration in bone marrow was detected in 1998 and was diagnosed as CLL with the coexistence of breast cancer. The patient died because of multiorgan failure and multiple metastasis including bone marrow in 2000.
BÜLENT KARABULUT1, GÜRAY SAYDAM1, MUSTAFA ÖZMEN1, ULUS ALİ ŞANLİ1, CANFEZA SEZGİN1, MİNE HEKİMGİL1, RÜÇHAN USLU1, ERDEM GÖKER1, FİLİZ BÜYÜKKEÇECİ1
Ege Üniversitesi Tip Fakültesi Hastanesi İç Hastalıkları Ana Bilim Dalı, İZMİR
Keywords: breast cancer, chronic lymphocytic leukemia
It is a rare phenomenon to detect the second malignancy in the course of malignant disease. The risk of secondary malignancy in CLL patients is significantly higher than normal population. Also, CLL can be detected as secondary malignancy in the course of other malignant diseases. In such cases, the common ethiological agent can be considered. In this report, we present a case who was diagnosed as breast cancer in 1996. After surgical resection, the patient was treated with radiotherapy and chemotherapy. During the follow-up period, lymphocytosis in peripheral blood and mature lymphocyte infiltration in bone marrow was detected in 1998 and was diagnosed as CLL with the coexistence of breast cancer. The patient died because of multiorgan failure and multiple metastasis including bone marrow in 2000.