International Journal of Hematology and Oncology 2019, Vol 29, Num 4 Page(s): 071-081
SERUM VITAMIN A LEVELS IN IRON DEFICIENCY ANEMIA AND THE EFFECT OF VITAMIN A SUPPLEMENT ON INTRAVENOUS IRON TREATMENT

MEHMET AKİF ÖZDEMİR1, DURAN ARSLAN1, MUSTAFA ÇALİK1

Erciyes Üniversitesi Tip Fakültesi Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, KAYSERİ

Keywords: anemia, iron deficiency, vitamin a
Iron deficiency anemia is one of the most frequent child health problem around the world. Interrelation between iron and vitamin A metabolism is well known. On the other hand there are several reports about the benefit of vitamin A supplementation during iron therapy. We studied 42 children whose ages between 6 mo to 13 years, 15 of them were female and 27 of them were male. First serum vitamin A and beta carotene levels were determined. They were divided randomly to two groups: First group received only intravenous iron hydroxyl sucrose and second group received intravenous iron hydroxyl sucrose plus single dose oral 200 000 U vitamin A at the start of the therapy. None of the 42 patients had low serum levels of vitamin A and/or beta carotene. There was no difference in hematological data at the start and 15th and 60th day of the therapy between two groups. It is concluded that vitamin A supplementation during intravenous iron therapy has no effect on the final hematological results and it is possibly related with the route of iron administration and/or vitamin A status of the patients.