International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 099-102
SPONTANEOUS REMISSION IN ACUTE LEUKEMIA: A REPORT OF TWO CASES
G. HAYRİ ÖZSAN1, FATİH DEMİRKAN1, İLHAN ÖZTOP1, M. ALİ ÖZCAN1, FİLİZ VURAL1, BÜLENT ÜNDAR1
Dokuz Eylül University, School of Medicine, Division of Hematology-Oncology, İZMİR
Keywords: spontaneous remission, acute myelocytic leukemia, acute lymphocytic leukemia
Spontaneous remission (SR) is very rarely observed in acute leukemias. We report one case of ALL and one case of AML evolving to SR. Both of our patients had serious documented hepatic infections at diagnosis. In serious infections the elevated levels of cytokines might show a negative proliferative effect on leukemic cells. Better understanding the pathophysiology of SR can help in developing new treatment strategies.
G. HAYRİ ÖZSAN1, FATİH DEMİRKAN1, İLHAN ÖZTOP1, M. ALİ ÖZCAN1, FİLİZ VURAL1, BÜLENT ÜNDAR1
Dokuz Eylül University, School of Medicine, Division of Hematology-Oncology, İZMİR
Keywords: spontaneous remission, acute myelocytic leukemia, acute lymphocytic leukemia
Spontaneous remission (SR) is very rarely observed in acute leukemias. We report one case of ALL and one case of AML evolving to SR. Both of our patients had serious documented hepatic infections at diagnosis. In serious infections the elevated levels of cytokines might show a negative proliferative effect on leukemic cells. Better understanding the pathophysiology of SR can help in developing new treatment strategies.